Harlequins 20 Leicester 23: Harlequins suffered a double-header of defeats over successive weekends against Leicester Tigers as they were edged out by three points on Saturday.
An entertaining game will be remembered for a breathtaking Ben Willis try - the chief architect was England Under 21 winger Ugo Monye who broke from his own 22, slipping past Leicester's Leon Lloyd and Andy Goode and running almost the length of the pitch, before neatly passing out of the tackle for Willis to dash over yards from the line.
With an earlier penalty this gave Quins a 10-0 lead on 11 minutes which, despite some impressive play, they squandered.
Two penalties from Leicester's Andy Goode and a Louis Deacon try put the visitors in the driving seat.
Another try soon followed for the visitors but Harlequins rallied and regained the lead the lead through Mel Deane when he touched down after a strong surging run for 20-18.
However, the lead did not last, former England player Austin Healey was fed from a scrum and sprinted clear to the try line for which was to be the decisive try 13 minutes before full time.
Quins boss Mark Evans, who has seen his side experience their third Zurich Premiership defeat on the trot leaving them seventh on 42 points, said: "Frustrated is a very good word to describe how I feel. I am massively frustrated.
"With four games to go, there are five teams close together in the league table and if we had won against Leicester we could have been in a strong position to push forward and guarantee our place in Europe next season. The result is very important and that is why I am frustrated.
Evans lamented: "The problem was we lost our concentration at key moments and we didn't execute at key times. Consequently we lost control of the game."
Quins scorers: tries - Willis, Deane; cons - Dunne 2; pens - Dunne 2.
Harlequins: Worsley (Jones, 49mins), Fuga, Gomez (Dawson, 49m), Rudzki (Davison, 49m), Evans, Tiatia (Sherriff, 76m), Vos, Diprose, Willis, Dunne, Keogh, Deane, Taumalolo, Monye, Duffy.
This Sunday Quins travel to London Irish (3pm).
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